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Tadfil 20 Mg (Tadalafil)

Medically reviewed by Sanjay Gangani, B.Pharm, CMO & Pharmacist

Active Ingredient Tadalafil
Indication Erectile Dysfunction
Manufacturer Zenlabs Ethica Ltd.
Strength:- 20mg
Packaging 4 Tablets in strip

Tadfil 20 Mg (Tadalafil)

Pack Size Price Price/unit Quantity Add To Cart
60 Tablet/s $60 $1.00/Pill
90 Tablet/s $89 $0.99/Pill
120 Tablet/s $118 $0.98/Pill

What is Tadfil 20 mg?

  • Tadfil 20 is a prescription tablet for erectile dysfunction in men.

  • Each tablet contains 20 mg of the active ingredient tadalafil.

  • Tadalafil belongs to the PDE-5 inhibitor drug class.

  • It is a generic equivalent of the branded medicine Cialis.

  • The tablets are manufactured by Zenlabs Ethica Ltd., India.

  • Tadfil 20 helps men achieve and maintain a firm erection.

  • It works only when you are sexually aroused.

  • It does not increase sexual desire or libido.

  • It does not protect against HIV or other sexually transmitted infections.

  • It is not a contraceptive and does not prevent pregnancy.

  • Tadalafil is also used for benign prostatic hyperplasia and pulmonary hypertension.

  • Do not confuse Tadfil with Tadafil, a similarly named Indian brand.

  • Vidalista 20 mg tablets are made by Ajanta Pharma Ltd.

  • Check the carton spelling and manufacturer name before use.

  • Use Tadfil 20 only for the condition your doctor prescribed.

How Tadfil 20 mg Works (Mechanism of Action)

The action happens in five simple steps:

  • Sexual stimulation triggers the release of nitric oxide in penile tissue.

  • Nitric oxide raises levels of a messenger called cyclic GMP (cGMP).

  • Cyclic GMP relaxes the smooth muscle inside the corpus cavernosum.

  • Relaxed muscle allows more blood to flow into the penis.

  • Increased blood flow produces and maintains a firm erection.

  • An enzyme called PDE-5 normally breaks down cGMP.

  • Tadalafil selectively blocks the PDE-5 enzyme.

  • Blocking PDE-5 keeps cGMP levels higher for longer.

  • Blood vessels stay relaxed and erection quality improves.

Key pharmacology facts:

  • Onset of effect is usually around 30 minutes.

  • Elimination half-life is approximately 17.5 hours.

  • Clinical effect can last up to 36 hours.

  • The liver enzyme CYP3A4 is the main metabolism pathway.

  • Excretion occurs mainly through faeces and partly through urine.

  • Without sexual stimulation, tadalafil produces no erection.

Dosage Guide

Always follow the dose written on your prescription.

Patient SituationRecommended DoseTimingMaximum Frequency
Adult men, as-needed ED10 mg starting dose; 20 mg if neededAt least 30 minutes before sexual activityOne dose in 24 hours
Dose range, as-needed ED5 mg, 10 mg or 20 mgAdjusted by response and toleranceOne dose in 24 hours
Once-daily ED treatment2.5 mg to 5 mg daily (lower strengths)Same time each dayOnce daily; Tadfil 20 is not a daily dose
Mild to moderate kidney impairmentNo routine change; doctor may start at 5 mgAs prescribedOne dose in 24 hours
Severe kidney impairmentMaximum 5 mgAs prescribedNot more than once in 72 hours
Mild to moderate liver impairmentMaximum 10 mgAs prescribedOne dose in 24 hours
Severe liver impairmentUse is not recommendedNot applicableNot applicable
Taking strong CYP3A4 inhibitorsMaximum 10 mgAs prescribedNot more than once in 72 hours
Taking alpha-blockersStart at the lowest doseOnly after the alpha-blocker dose is stableOne dose in 24 hours
Older men aged 65 and aboveNo routine change neededAs prescribedOne dose in 24 hours
Women and anyone under 18Not indicated; do not useNot applicableNot applicable

Missed dose and overdose rules:

  • Tadfil 20 is taken as needed, so missed doses rarely apply.

  • If you take it daily, take the missed dose when remembered.

  • Skip the missed dose if the next dose is near.

  • Never take two tablets to make up for one.

  • Never exceed one 20 mg tablet in 24 hours.

  • Contact a doctor or poison centre immediately after a suspected overdose.

How to Take Tadfil 20 mg

  • Take one tablet by mouth with a glass of water.

  • Swallow the tablet whole and do not crush or chew it.

  • Take it about 30 to 60 minutes before sexual activity.

  • You may take it with or without food.

  • Wait for sexual stimulation, as the tablet alone will not work.

  • Allow at least 24 hours between two doses.

  • Do not split a 20 mg tablet unless your doctor advises it.

  • Do not combine it with any other ED medicine.

  • Tell your doctor if erections remain poor after several attempts.

  • A heavy, fatty meal may slightly delay the feeling of onset.

  • Some men plan a dose for the weekend due to long duration.

  • Keep alcohol intake low to avoid dizziness and low blood pressure.

  • Stop sexual activity and seek help if chest pain occurs.

Precautions

Absolute Contraindications – Do Not Use Tadfil 20 If You:

  • Take any nitrate medicine, regularly or occasionally.

  • Use nitroglycerin, isosorbide mononitrate or isosorbide dinitrate.

  • Use recreational nitrites known as “poppers” (amyl or butyl nitrite).

  • Take riociguat or another soluble guanylate cyclase stimulator.

  • Are allergic to tadalafil or any tablet ingredient.

  • Had a heart attack within the last 90 days.

  • Had a stroke within the last six months.

  • Have unstable angina or angina during sexual intercourse.

  • Have uncontrolled high or very low blood pressure.

  • Have severe heart failure or uncontrolled irregular heartbeat.

  • Were told that sexual activity is unsafe for your heart.

  • Have lost vision before due to non-arteritic ischaemic optic neuropathy.

  • Are a woman, a child or a teenager below 18 years.

Conditions You Must Disclose to Your Doctor

  • Any heart disease, chest pain, valve problem or past bypass surgery.

  • High blood pressure or low blood pressure.

  • Kidney disease or a history of dialysis.

  • Liver disease, hepatitis or cirrhosis.

  • Diabetes, especially if it is poorly controlled.

  • Stomach ulcers or any bleeding disorder.

  • Sickle cell anaemia, leukaemia or multiple myeloma.

  • Any penile deformity, such as Peyronie’s disease or curvature.

  • A previous erection lasting more than four hours.

  • Retinitis pigmentosa or any inherited eye disease.

  • Sudden vision loss or hearing loss in the past.

  • Benign prostatic hyperplasia or ongoing prostate treatment.

  • Recent surgery or planned surgery of any type.

  • All prescription, herbal and over-the-counter products you use.

Food and Drink Precautions

  • Food does not meaningfully change tadalafil absorption.

  • Avoid grapefruit and grapefruit juice while using this medicine.

  • Grapefruit can raise tadalafil blood levels and side effect risk.

  • Limit alcohol, as it worsens dizziness and lowers blood pressure.

  • Avoid heavy drinking on the day you take a tablet.

  • Very fatty meals may delay the onset of the effect.

  • Avoid pomelo juice and Seville orange products as a precaution.

  • Take the tablet with plain water, not with alcohol.

Before-Use Safety Checklist

  • Do you hold a valid prescription for Tadfil 20 mg?

  • Have you confirmed you take no nitrate medicine of any type?

  • Have you confirmed you do not take riociguat?

  • Has your doctor confirmed your heart can handle sexual activity?

  • Have you listed all your medicines for the doctor or pharmacist?

  • Have you disclosed any kidney or liver disease?

  • Have you checked you took no other ED tablet in 24 hours?

  • Have you checked the expiry date on the blister?

  • Is the blister sealed, undamaged and correctly stored?

Common and Less Common Side Effects

Most side effects are mild and settle without treatment.

Side EffectFrequencyWhat It Feels LikeWhat to Do
HeadacheCommonDull ache, often within hours of the doseRest and drink water; tell your doctor if severe
Indigestion or acid refluxCommonBurning or discomfort in the upper stomachAvoid spicy food; ask about an antacid
Back painCommonAching low back, often after 12 to 24 hoursUsually settles in 48 hours; report if persistent
Muscle pain (myalgia)CommonAching thighs, arms or general body acheRest; report pain that does not ease
Nasal congestionCommonBlocked or stuffy noseUsually mild; ask a pharmacist before using sprays
FlushingCommonWarm, red face, neck or chestUsually short-lived; keep cool
Pain in arms or legsCommonAching limbs after the doseRest; report if it repeats each time
DizzinessLess commonLight-headed feeling on standing upStand slowly; avoid driving until clear
Blurred visionLess commonSlightly hazy or unclear visionStop use and contact your doctor
Colour vision changeLess commonBlue tinge or altered colour perceptionStop use and contact your doctor
Eye redness or painLess commonRed, sore or watery eyesContact your doctor if it persists
Eyelid swellingLess commonPuffy eyelids after the doseReport to your doctor
Low blood pressureLess commonWeakness, fainting feelingSit or lie down; seek medical advice
Fast or irregular heartbeatLess commonPounding or fluttering in the chestSeek prompt medical advice
Nausea or abdominal painLess commonUpset stomach or crampingTake with light food; report if severe
Skin rash or itchingLess commonRed, itchy patches on the skinStop use and contact your doctor
Excessive sweatingLess commonUnusual sweating after the doseReport if troublesome
FatigueLess commonUnusual tirednessRest; report if it continues
Ringing in the earsLess commonBuzzing or ringing soundStop use and seek medical advice
Prolonged erectionRareErection lasting over four hoursEmergency – see Section 8 immediately
Sudden vision lossRareLoss of sight in one or both eyesEmergency – stop use and get urgent care
Sudden hearing lossRareHearing drops suddenly, often one sideEmergency – stop use and get urgent care

Drug Interactions – Avoid or Use With Caution

Never combine Tadfil 20 with these:

  • Nitrates: nitroglycerin, isosorbide mononitrate, isosorbide dinitrate.

  • Nitrate sprays, patches, ointments and sublingual tablets.

  • Recreational nitrites, commonly sold as “poppers”.

  • Riociguat and other guanylate cyclase stimulators.

  • Other PDE-5 inhibitors: sildenafil, vardenafil, avanafil, udenafil.

  • Any other tadalafil product, including daily-dose brands.

Use only with medical supervision:

  • Alpha-blockers: doxazosin, tamsulosin, alfuzosin, terazosin.

  • Blood pressure medicines, including amlodipine and enalapril.

  • Diuretics such as bendroflumethiazide.

  • Strong CYP3A4 inhibitors: ketoconazole, itraconazole, ritonavir.

  • Macrolide antibiotics such as clarithromycin and erythromycin.

  • CYP3A4 inducers: rifampicin, phenytoin, carbamazepine, phenobarbital.

  • St John’s wort, which can reduce the medicine’s effect.

  • Alcohol in large amounts, due to added blood pressure drop.

  • Grapefruit juice, which can raise tadalafil blood levels.

Interaction outcomes to understand:

  • Nitrates plus tadalafil can cause a dangerous fall in blood pressure.

  • Alpha-blockers plus tadalafil can cause fainting on standing.

  • CYP3A4 inhibitors raise tadalafil levels and side effect risk.

  • CYP3A4 inducers lower tadalafil levels and reduce effectiveness.

Emergency Warning Signs – Seek Urgent Medical Help

Call emergency services or go to hospital immediately if you have:

  • An erection lasting longer than four hours (priapism).

  • A painful erection of any duration.

  • Sudden loss of vision in one or both eyes.

  • Sudden decrease or loss of hearing, with or without ringing.

  • Chest pain, pressure or tightness during or after sex.

  • Pain spreading to the jaw, neck, shoulder or left arm.

  • Severe dizziness, fainting or collapse.

  • Shortness of breath at rest or with light effort.

  • Irregular, racing or pounding heartbeat.

  • Swelling of the face, lips, tongue or throat.

  • Widespread rash, hives or difficulty breathing or swallowing.

  • Seizure or sudden confusion.

  • Numbness or weakness on one side of the body.

  • Tell every treating doctor that you took tadalafil.

  • State the exact time and dose you took.

  • Nitrates must not be given within 48 hours of tadalafil.

  • Priapism needs treatment within hours to protect penile tissue.

Why Choose Tadfil 20 mg?

  • Long action window of up to 36 hours after one tablet.

  • Fast onset, with effects often felt within 30 minutes.

  • Food does not meaningfully affect how well it is absorbed.

  • Flexible timing removes the pressure of a narrow dosing window.

  • Contains the same active molecule as branded Cialis.

  • Generic pricing makes long-term therapy more affordable.

  • Tadalafil is backed by large, long-running clinical trial data.

  • Well-defined safety profile documented in regulatory labels.

  • Single daily tablet keeps the routine simple.

  • Blister packaging protects tablets from moisture and light.

  • Manufactured by Zenlabs Ethica Ltd., an Indian pharmaceutical company.

Honest balance for the buyer:

  • Tadfil 20 does not cure erectile dysfunction.

  • It treats the symptom while the underlying cause remains.

  • ED can signal heart disease or diabetes, so get assessed.

  • A valid prescription and medical review remain essential.

Storage Instructions

  • Store at controlled room temperature, ideally 20°C to 25°C.

  • Brief excursions between 15°C and 30°C are acceptable.

  • Keep tablets in the original blister until use.

  • Protect from direct sunlight, heat and moisture.

  • Do not store in the bathroom or near a sink.

  • Do not refrigerate or freeze the tablets.

  • Keep the pack out of sight and reach of children.

  • Keep away from pets at all times.

  • Check the expiry date printed on the blister and carton.

  • Do not use tablets that are chipped, discoloured or damp.

  • Do not transfer tablets into unlabelled containers.

  • Do not flush unused tablets down the toilet.

  • Return expired medicine to a pharmacy take-back scheme.

Sanjay Gangani

Sanjay Gangani

B.Pharm, CMO & Pharmacist

Licensed pharmacist (B.Pharm) with 12+ years in clinical pharmacy and patient care. Reviews every article for evidence-based accuracy before it is published on ACTIZA Store.

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