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Tadarise Oral Jelly (Tadalafil)
Medically reviewed by Sanjay Gangani, B.Pharm, CMO & Pharmacist
| Active Ingredient | Tadalafil |
|---|---|
| Indication | Erectile Dysfunction |
| Manufacturer | Sunrise Remedies Pvt Ltd |
| Strength:- | 20mg |
| Packaging | 7 x 5g Sachets in Box |
Tadarise Oral Jelly (Tadalafil) | ||||
|---|---|---|---|---|
| Pack Size | Price | Quantity | Add To Cart | |
| 30 Sachet/s | $42 | |||
| 60 Sachet/s | $72 | |||
| 90 Sachet/s | $100 | |||
What is Tadarise Oral Jelly?
How It Works (Mechanism of Action)
What the jelly format does not change
Dosage Guide
A doctor sets the dose. This reflects approved tadalafil labelling.
| Situation | Licensed dose | Frequency | Does this sachet fit? |
|---|---|---|---|
| Established on 20 mg and tolerating it | 20 mg | Once in 24 hours | Yes. This is the intended user. |
| First time taking tadalafil | 10 mg | Once in 24 hours | No. Start on a 10 mg tablet. |
| 10 mg worked but caused headache | 5 mg | Once in 24 hours | No. Four times the needed dose. |
| Wanting a daily routine instead | 2.5 to 5 mg | Every day | No. Wrong strength and wrong regimen. |
| Prostate and urinary symptoms | 5 mg | Every day | No. Wrong strength and wrong regimen. |
| Raised lung artery pressure | 40 mg | Every day, specialist care | No. Half the required dose. See Finding 3. |
| Moderate kidney impairment | 10 mg maximum | Once in 48 hours | No. Double the ceiling. |
| Severe kidney impairment | 5 mg maximum | Once in 72 hours | No. Four times the ceiling. |
| Mild or moderate liver impairment | 10 mg maximum | Once in 24 hours | No. Double the ceiling. |
| Severe liver impairment | Not recommended | Not applicable | No. Do not use. |
| On potent CYP3A4 inhibitors | 10 mg maximum | Once in 72 hours | No. Double the ceiling. |
| Aged over 65 | No change for age alone | Once in 24 hours | Possibly. Sensitivity may be greater. |
| Women, children, under-18s | Not indicated | Not applicable | No. |
How to Take It
Why diluting it is a bad idea
Missed doses
Precautions
Absolute contraindications
Tell your doctor about
Food, drink and the gel itself
Before-use checklist
Side Effects
| Effect | Placebo | 10 mg | 20 mg |
|---|---|---|---|
| Headache | 5% | 11% | 15% |
| Indigestion | 1% | 8% | 10% |
| Back pain | 3% | 5% | 6% |
| Muscle ache | 1% | 4% | 3% |
| Blocked nose | 1% | 3% | 3% |
| Flushing | 1% | 3% | 3% |
| Limb pain | 1% | 3% | 3% |
The delayed backache
Uncommon and rare effects
| Where | What has been reported |
|---|---|
| Circulation | Chest discomfort, palpitations, racing pulse, low pressure, fainting |
| Circulation, rare | Heart attack, sudden cardiac death, stroke |
| Vision | Blurring, altered colour, sore or red eyes, swollen lids |
| Vision, rare | NAION, blocked retinal vessels, visual field loss |
| Hearing | Tinnitus, sudden partial or complete hearing loss |
| Head and nerves | Dizziness, vertigo, sleeplessness, numbness, migraine, seizure, memory blanks |
| Stomach and gut | Dry mouth, nausea, vomiting, reflux, gastritis, altered liver blood tests |
| Joints and muscle | Aching joints, stiff neck, cramping |
| Genital and urinary | Prolonged erection, priapism, unprompted erections, kidney impairment |
| Breathing | Breathlessness, nosebleeds, sore throat |
| Skin | Rash, itch, sweating, nettle rash |
| Skin, rare | Stevens-Johnson syndrome, peeling dermatitis |
Drug Interactions – Avoid With
| Severity | Substance | Consequence |
|---|---|---|
| ABSOLUTE BAN | Nitrates in any form: tablets, sprays, patches, ointments | Blood pressure can collapse. Deaths have occurred. |
| ABSOLUTE BAN | Poppers: amyl nitrite and similar | Identical danger |
| ABSOLUTE BAN | Riociguat and guanylate cyclase stimulators | Unsafe blood pressure fall |
| ABSOLUTE BAN | Sildenafil, vardenafil or another PDE-5 inhibitor | No added benefit, compounded pressure drop |
| ABSOLUTE BAN | Any other tadalafil product, tablet or jelly | Silent doubling of the dose |
| DOSE CONFLICT | Ketoconazole 400 mg daily | Exposure rises 312%; ceiling becomes 10 mg per 72 hours |
| DOSE CONFLICT | Ritonavir 200 mg twice daily | Exposure rises 124%; ceiling becomes 10 mg per 72 hours |
| DOSE CONFLICT | Itraconazole and other strong CYP3A4 blockers | Ceiling becomes 10 mg. This sachet is 20 mg. |
| CAUTION | Alpha-blockers: doxazosin, tamsulosin, alfuzosin | Dizziness, fainting, low pressure on standing |
| NOT RECOMMENDED | Alpha-blockers where BPH is the condition treated | The pairing was not adequately studied |
| CAUTION | Blood pressure medicines including ARBs | A further fall of roughly 8/4 mmHg |
| CAUTION | Alcohol, five drinks or more | Dizziness, headache, low pressure on standing |
| WEAKENS IT | Rifampicin | Exposure falls 88%. The sachet may not work. |
| WEAKENS IT | Bosentan, carbamazepine, phenytoin, phenobarbital | Exposure falls |
| MINOR | Antacids | Slower absorption, unchanged total exposure |
| MINOR | Grapefruit juice | Raises exposure |

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