Misoprost 25 Mg (Misoprostol)

What is Misoprost 25 mcg?

How Misoprostol Works (Mechanism of Action)

The action happens in five simple steps:

Why low doses are used for induction:

How the body handles it:

Dosage and Administration

Dosing is set by the hospital’s obstetric protocol. Examples below are from published sources.

Setting or Source	What It Describes	Timing	Key Note
WHO-prequalified vaginal label	25 micrograms vaginally	Every 4 to 6 hours	Maximum of 4 to 6 tablets
NHS Wales oral protocol	25 micrograms orally	Up to every 2 hours	Maximum 200 micrograms in 24 hours
Registered clinical trial	25 micrograms vaginally	Every 6 hours	Maximum 200 micrograms
Cochrane review	20 to 25 micrograms orally	As per protocol	Oral preferred over vaginal for safety
Route for this product	Not confirmed from the listing	Check the pack	Vaginal absorption is about three times oral
Who gives it	A doctor or midwife	In hospital only	With monitoring of mother and baby
With oxytocin at the same time	Contraindicated	Not applicable	Misoprostol increases oxytocin’s effect
After a previous caesarean	Contraindicated in the WHO label	Not applicable	Risk of the womb rupturing
First-trimester exposure	Not this indication	Not applicable	About threefold higher risk of birth defects
Under 18 years of age	Not established	Not applicable	No data in the WHO label

How to read this table:

Overdose:

How It Is Given

What to tell the midwife or doctor at once:

Precautions

Contraindications in the WHO-Prequalified Label

Conditions Needing Caution

Food and Other Practical Points

Clinical Checklist Before Use

Side Effects and Risks

Effects reported in the WHO-prequalified label:

Effect	Category	What It Means	What Happens Next
Nausea or vomiting	Common	Feeling or being sick	Reported to the midwife
Diarrhoea	Common	Loose stools	Usually short-lived
Abdominal pain	Common	Cramping pain	Expected with contractions
Fever or shivering	Occasional	Raised temperature, chills	Monitored by the team
Headache or dizziness	Occasional	Head pain or light-headedness	Reported to the midwife
Low blood pressure	Occasional	Faintness	Monitored by the team
Contractions too strong or frequent	Serious	Can reduce the baby’s heart rate	Dose stopped; delivery may be expedited
Womb rupture	Serious	A tear in the wall of the womb	Emergency surgery
Placental abruption	Serious	The placenta separates early	Emergency care
Amniotic fluid embolism	Serious	A rare, life-threatening reaction	Intensive care
Cardiac arrest	Serious	The heart stops	Emergency resuscitation
Severe allergic reaction	Serious	Swelling, breathing difficulty	Emergency treatment

Effects on the baby reported in the label:

After induction:

Drug Interactions

Contraindicated:

Use with caution:

Not expected to interact:

Emergency Warning Signs

In hospital, tell the team immediately about:

Outside hospital:

Role of This Medicine, and Its Limits

What misoprostol 25 micrograms offers in hospital:

Why this is not an online retail product:

Storage Instructions