FEMALEFIL 10 MG (Tadalafil) Medically reviewed by Sanjay Gangani, B.Pharm, CMO & Pharmacist
Active Ingredient Tadalafil Indication Erectile Dysfunction Manufacturer RSM Enterprises Strength:- 10mg Packaging 10 tablets in 1 strip
INQUIRE ABOUT FEMALEFIL 10 MG (Tadalafil)
What is Femalefil 10 mg? Femalefil 10 is a tablet containing 10 mg of tadalafil .
Tadalafil is a PDE-5 inhibitor, the molecule found in Cialis.
The brand is marketed to women, as the name indicates.
Listings name RSM Enterprises, Sunrise Remedies or a Delhi exporter.
No manufacturer datasheet supporting a female indication could be found.
Erectile dysfunction in adult men.
Symptoms of an enlarged prostate in adult men.
Raised pressure in the lung arteries, under a different brand and dose.
That is the complete list, in every country.
No female indication appears in any approval anywhere.
10 mg is the dose a man begins on when treating erectile dysfunction.
It is raised to 20 mg only if 10 mg proves insufficient.
The figure was set in dose-ranging studies conducted in men.
It has never been tested for effectiveness or safety in women.
Other brands sell the same molecule to women at 20 mg.
Neither figure has more female evidence behind it than the other.
What tadalafil does, in anyone It relaxes the smooth muscle in the walls of blood vessels.
Vessels widen and blood flow through them increases.
PDE-5 enzymes do exist in female genital tissue.
So a local blood flow effect in women is biologically plausible.
That plausibility is why the research was attempted at all.
The research has not settled whether it produces a useful result.
It cannot create sexual desire. Desire arises in the brain.
Tadalafil does not act on the brain pathways involved.
It cannot alter hormone levels of any kind.
It cannot restore tissue thinned by the menopause.
It cannot treat infection, endometriosis, fibroids or cysts.
It cannot relieve pain arising from any of those.
It cannot address anxiety, low mood or relationship difficulty.
It offers no protection against sexually transmitted infections.
How It Works (Mechanism of Action) Stated correctly, because one circulating version has it backwards.
Sexual stimulation releases nitric oxide into genital tissue.
Nitric oxide prompts production of a messenger called cGMP.
cGMP relaxes the smooth muscle lining local blood vessels.
Those vessels widen and blood flow increases.
PDE-5 is the enzyme that breaks cGMP down.
Tadalafil blocks PDE-5. It does not break cGMP down itself.
Blocking PDE-5 means cGMP persists and the effect is sustained.
The step that limits what this can achieve Look again at step one. It requires sexual stimulation to already be happening.
The drug amplifies a response that has already begun.
It cannot initiate one.
A woman whose difficulty is absent desire has nothing to amplify.
A woman whose difficulty is pain has a different problem entirely.
The narrow group this could theoretically help is smaller than the marketing suggests.
It would be a woman with normal desire and a poor physical response.
Even for her, the trial evidence remains unsettled.
All figures below come from studies in men. No female data exists.
Peak blood level occurs between 30 minutes and 6 hours, median 2 hours.
The terminal half-life is about 17.5 hours.
Food does not affect absorption.
The liver clears it, mainly through the enzyme CYP3A4.
Tadalafil is over 10,000 times more selective for PDE-5 than PDE-3.
It is 700 times more selective for PDE-5 than retinal PDE-6.
Colour vision changes are therefore rare, under 0.1 percent in men.
Dosage Guide The key row in this table is the first one, and it is empty.
Population Approved dose Frequency Basis for the figure Women, any age, any indication NONE ESTABLISHED Not applicable No study, no approval Adult men, ED, starting dose 10 mg Once in 24 hours Male dose-ranging studies Adult men, ED, maximum 20 mg Once in 24 hours Male dose-ranging studies Adult men, ED, daily regimen 2.5 to 5 mg Every day Approved labelling Adult men, prostate symptoms 5 mg Every day Approved labelling Lung artery pressure 40 mg Every day Separate brand, specialist care Children and adolescents Not indicated Not applicable No approval
How to Take It Practical points if a doctor has prescribed this for you.
Confirm the prescription is for you personally, from a doctor who knows your history.
Confirm the doctor knows tadalafil is not approved for women.
Ask whether an approved treatment would suit your particular difficulty.
Check the strip is sealed and within its expiry date.
Swallow the tablet whole with water.
Do not split or crush it.
Food makes no difference to absorption.
Take it about an hour before, if timing around activity.
Take one tablet only, and nothing further for 24 hours.
Ignore any review suggesting two doses per occasion.
Pregnancy and breastfeeding Tell your doctor if you are pregnant, might become pregnant, or are breastfeeding.
The approved label states tadalafil is not indicated for use in females.
Data on its use in pregnancy is limited.
The same applies while breastfeeding.
This conversation belongs before the first tablet, not after.
Decide in advance what improvement would actually look like for you.
Vague hopes are impossible to assess and easy to be disappointed by.
Give it several separate occasions rather than one.
Keep other factors steady: alcohol, tiredness, and setting.
If nothing changes, that is useful information for your doctor.
It suggests the difficulty is not one that blood flow addresses.
That points towards a different assessment, not a higher dose.
Precautions These derive from the male safety data. No female safety data exists.
Absolute contraindications Nitrate medicines of any kind, regular or occasional.
Nitroglycerin, isosorbide mononitrate and isosorbide dinitrate.
Sprays, patches and ointments count as much as tablets.
Recreational nitrites known as poppers.
Riociguat or another guanylate cyclase stimulator.
Known serious allergy to tadalafil under any brand name.
Severe liver impairment, graded Child-Pugh C.
Anyone under 18 years of age.
Tell your doctor about Pregnancy, planned pregnancy or breastfeeding.
Any heart condition, including rhythm problems and heart failure.
A heart attack or stroke in the past six months.
Blood pressure that is low, or high and uncontrolled.
Any history of fainting.
Liver or kidney impairment of any degree.
Retinitis pigmentosa or any sudden vision loss in the past.
Bleeding disorders or an active stomach ulcer.
Migraine, which vasodilators can aggravate.
Diabetes, which affects sexual function in women as well as men.
Whether you have gone through the menopause.
Any pain during sex, and where you feel it.
Any antidepressant you take, which commonly affects sexual function.
Every other medicine, including anything bought over a counter.
Food and drink Food does not affect absorption.
Avoid grapefruit and grapefruit juice, which raise tadalafil levels.
Keep alcohol low. Both alcohol and tadalafil widen blood vessels.
Together they can cause dizziness and low pressure on standing.
Alcohol also blunts sexual response independently.
Never combine this with poppers in any setting.
Before-use checklist Has a doctor prescribed this to me personally, knowing I am a woman?
Does that doctor know tadalafil is not approved for women?
Have we identified which difficulty I actually have?
If I have pain during sex, has that been investigated properly?
Have we discussed the approved alternatives first?
Am I pregnant, planning pregnancy, or breastfeeding?
Am I certain I take no nitrate, including a spray or patch?
Am I free of riociguat and of poppers?
Have I declared my heart, liver, kidney and eye history?
Has my doctor seen a full list of my medicines?
Do I understand what this drug cannot do?
Do I know the emergency signs in Section 8?
Side Effects All figures below come from trials in men. Rates in women are unknown.
Effect Placebo 10 mg 20 mg Headache 5% 11% 15% Indigestion 1% 8% 10% Back pain 3% 5% 6% Muscle ache 1% 4% 3% Blocked nose 1% 3% 3% Flushing 1% 3% 3% Limb pain 1% 3% 3%
The 10 mg column is the relevant one for this product.
Headache affected about one man in nine at this dose.
Indigestion affected about one in twelve.
Rates at 10 mg are meaningfully lower than at 20 mg.
There is no reason to assume women are immune to these effects.
There is also no data showing the rates are the same in women.
Body size, hormone levels and drug handling all differ between sexes.
Uncommon and rare effects Where What has been reported in men Circulation Chest discomfort, palpitations, racing pulse, low pressure, fainting Circulation, rare Heart attack, sudden cardiac death, stroke Vision Blurring, altered colour, sore or red eyes, swollen lids Vision, rare NAION, blocked retinal vessels, visual field loss Hearing Tinnitus, sudden partial or complete hearing loss Head and nerves Dizziness, vertigo, sleeplessness, migraine, seizure, memory blanks Stomach and gut Dry mouth, nausea, vomiting, reflux, gastritis, altered liver tests Joints and muscle Aching joints, stiff neck, cramping Skin Rash, itch, sweating, nettle rash Skin, rare Stevens-Johnson syndrome, peeling dermatitis
Drug Interactions – Avoid With Severity Substance Consequence ABSOLUTE BAN Nitrates in any form, including sprays and patches Blood pressure can fall to a fatal level ABSOLUTE BAN Poppers: amyl nitrite and similar Identical danger ABSOLUTE BAN Riociguat and guanylate cyclase stimulators Unsafe blood pressure fall ABSOLUTE BAN Any other PDE-5 inhibitor or tadalafil product Silent doubling of the dose DOSE CONFLICT Ketoconazole, itraconazole, ritonavir Exposure rises steeply. Male ceiling becomes 10 mg per 72 hours. CAUTION Blood pressure medicines and ARBs A further fall of roughly 8/4 mmHg CAUTION Alpha-blockers Dizziness, fainting, low pressure on standing CAUTION Alcohol, in quantity Dizziness, headache, low pressure on standing CAUTION Flibanserin, if prescribed for low desire Both can cause fainting and low blood pressure WEAKENS IT Rifampicin, carbamazepine, phenytoin, phenobarbital Exposure falls sharply MINOR Antacids Slower absorption, unchanged total exposure MINOR Grapefruit juice Raises exposure
The flibanserin row matters if you are already treated for low desire.
Flibanserin carries its own fainting and blood pressure warnings.
Combining it with a vasodilator has not been studied.
Tell your doctor about every medicine, in writing.
Emergency Warning Signs Stop and get urgent medical help if any of these occur:
Fainting, or feeling that you are about to faint.
Sudden loss of vision in one eye or both.
Sudden loss or reduction of hearing, with or without ringing.
Chest pain , tightness, or pain into arm, neck or jaw.
Severe dizziness on standing.
Slurred speech, a drooping face, or one-sided weakness.
Swelling of the lips, tongue, face or throat.
A rash that spreads, blisters or peels.
A seizure.
A severe headache that does not settle.
Why Choose Femalefil 10 mg Written honestly, because the evidence does not support a sales pitch.
What can honestly be said It contains tadalafil, a well-characterised molecule with 20 years of male data.
PDE-5 enzymes are present in female genital tissue.
A local blood flow effect in women is therefore biologically plausible.
10 mg is a lower exposure than the 20 mg products sold for the same purpose.
Side effects at 10 mg were consistently lower than at 20 mg in men.
A doctor may reasonably choose to try it off-label in a selected patient.
That decision belongs to a doctor who knows the individual.
What cannot honestly be said It is not approved for women anywhere in the world.
It is not proven to treat any female sexual difficulty.
It does not treat pain during sex, and should not be sold as doing so.
It does not increase desire, by mechanism.
It does not support orgasm or amplify pleasure in any proven way.
It has no established dose in women, at 10 mg or any other figure.
It has no established safety profile in women.
It is not a treatment for male erectile dysfunction in this packaging, whatever some listings say.
Storage Instructions Keep below 30 °C.
US tadalafil labelling gives 25 °C, tolerating 15 to 30 °C.
Leave tablets sealed in the blister until use.
Keep away from direct sunlight, heat and damp.
Do not refrigerate, and never freeze.
Bathrooms and parked cars are the two worst places.
Store out of the reach of children.
Discard any tablet that is chipped, faded or crumbling.
Do not use past the printed expiry date.
Return unused tablets to a pharmacy.
Never share this medicine with anyone else.
Sanjay Gangani
B.Pharm, CMO & Pharmacist
Licensed pharmacist (B.Pharm) with 12+ years in clinical pharmacy and patient care. Reviews every article for evidence-based accuracy before it is published on ACTIZA Store.
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