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Tadarise Oral Jelly (Tadalafil)

Medically reviewed by Sanjay Gangani, B.Pharm, CMO & Pharmacist

Active Ingredient Tadalafil
Indication Erectile Dysfunction
Manufacturer Sunrise Remedies Pvt Ltd
Strength:- 20mg
Packaging 7 x 5g Sachets in Box

Tadarise Oral Jelly (Tadalafil)

Pack Size Price Price/unit Quantity Add To Cart
30 Sachet/s $42 $1.40/Pill
60 Sachet/s $72 $1.20/Pill
90 Sachet/s $100 $1.11/Pill

What is Tadarise Oral Jelly?

  • Tadarise Oral Jelly is a prescription treatment for erectile dysfunction.

  • Each sachet contains a gel holding 20 mg of tadalafil.

  • Tadalafil is the molecule found in Cialis.

  • Sunrise Remedies Pvt Ltd of India manufactures it.

  • The manufacturer lists orange as the flavour.

  • Resellers describe other fruit flavours as well.

  • Each sachet is a single dose, squeezed into the mouth and swallowed.

  • Men already established on Tadarise 5 mg of tadalafil.

  • And who find swallowing tablets unpleasant or difficult.

  • That second condition is the whole reason the format exists.

  • A man happy with tablets gains nothing by switching to a jelly.

How It Works (Mechanism of Action)

  • Sexual arousal releases nitric oxide into the erectile tissue.

  • Nitric oxide prompts production of a messenger called cGMP.

  • cGMP relaxes the smooth muscle lining the penile arteries.

  • Relaxed arteries widen and fill with blood.

  • An enzyme called PDE-5 continually breaks cGMP down.

  • Tadalafil occupies PDE-5 and halts that breakdown.

  • cGMP accumulates and the erection improves.

  • It removes the need to swallow a solid object. That is the real benefit.

  • It removes the need for water, which helps men with dry mouth.

  • It removes the bitter taste, which masks the drug.

  • Those three things are genuine and worth paying for if you need them.

What the jelly format does not change

  • Tadarise 20 mg dissolves in the mouth and is then swallowed.

  • Absorption happens in the gut, exactly as with a tablet.

  • Tadalafil is practically insoluble in water.

  • It cannot cross the lining of the mouth in any meaningful amount.

  • So the drug does not bypass digestion, whatever a product page says.

  • Duration, side effects, contraindications and interactions are identical.

  • One honest supplier states exactly that, and is right to.

  • Sildenafil jellies make the same fast-absorption claim.

  • For sildenafil the claim is at least chemically plausible.

  • Sildenafil citrate dissolves in water at 3.5 mg per millilitre.

  • Tadalafil does not dissolve, so the same reasoning fails here.

  • The limiting factor is the molecule, not the format.

Dosage Guide

A doctor sets the dose. This reflects approved tadalafil labelling.

SituationLicensed doseFrequencyDoes this sachet fit?
Established on 20 mg and tolerating it20 mgOnce in 24 hoursYes. This is the intended user.
First time taking tadalafil10 mgOnce in 24 hoursNo. Start on a 10 mg tablet.
10 mg worked but caused headache5 mgOnce in 24 hoursNo. Four times the needed dose.
Wanting a daily routine instead2.5 to 5 mgEvery dayNo. Wrong strength and wrong regimen.
Prostate and urinary symptoms5 mgEvery dayNo. Wrong strength and wrong regimen.
Raised lung artery pressure40 mgEvery day, specialist careNo. Half the required dose. See Finding 3.
Moderate kidney impairment10 mg maximumOnce in 48 hoursNo. Double the ceiling.
Severe kidney impairment5 mg maximumOnce in 72 hoursNo. Four times the ceiling.
Mild or moderate liver impairment10 mg maximumOnce in 24 hoursNo. Double the ceiling.
Severe liver impairmentNot recommendedNot applicableNo. Do not use.
On potent CYP3A4 inhibitors10 mg maximumOnce in 72 hoursNo. Double the ceiling.
Aged over 65No change for age aloneOnce in 24 hoursPossibly. Sensitivity may be greater.
Women, children, under-18sNot indicatedNot applicableNo.

How to Take It

  • Confirm with a doctor that 20 mg is the right strength for you.

  • Check the sachet is sealed and within its expiry date.

  • Tear along the notch at the top.

  • Squeeze the entire contents into your mouth, or onto a spoon.

  • Swallow it. Water is optional, not required.

  • Do not stir it into a soft drink, juice or anything else.

  • Take it at least 30 minutes before activity.

  • An hour ahead suits most men better.

  • Eat normally. Food makes no difference at all.

  • Wait for arousal. The gel does nothing without it.

  • Use one sachet and discard any leftover gel.

  • Take nothing further for a full 24 hours.

Why diluting it is a bad idea

  • The 20 mg is spread through the whole gel, not concentrated in part of it.

  • Stirring it into a drink leaves some behind in the glass.

  • You then take an unknown fraction of the dose.

  • You cannot tell whether you took 20 mg, 15 mg or less.

  • One product page advises diluting it. Ignore that advice.

  • The same page contradicts itself two sentences later.

  • Some men with severe dysphagia struggle with liquids and gels too.

  • Thin liquids can be harder to control than thick ones.

  • Sit fully upright before taking it, and stay upright afterwards.

  • Take it in small amounts rather than all at once if needed.

  • Stop and seek advice if you cough or choke while taking it.

  • Coughing on swallowing suggests material entering the airway.

  • That needs medical assessment, not a change of flavour.

Missed doses

  • This is taken when needed, so nothing can be missed.

  • Never take a second sachet within 24 hours.

  • Never take extra to compensate for a disappointing result.

  • If you have taken several, go to a hospital emergency department.

Precautions

Absolute contraindications

  • Nitrate medicines of any kind, regular or occasional.

  • Nitroglycerin, isosorbide mononitrate and isosorbide dinitrate.

  • Sprays, patches and ointments count as much as tablets.

  • Recreational nitrites known as poppers.

  • Riociguat or another guanylate cyclase stimulator.

  • Known serious allergy to tadalafil under any brand.

  • Known allergy to the flavouring or colouring in the gel.

  • Any case where a doctor has said sex is unsafe for your heart.

  • Severe liver impairment, graded Child-Pugh C.

  • Use by women or anyone under 18.

Tell your doctor about

  • Any recent or long-standing difficulty swallowing.

  • Any stroke, particularly within the past six months.

  • Parkinson’s disease or another neurological condition.

  • Treatment for head or neck cancer.

  • Severe or long-standing acid reflux.

  • A heart attack within the past 90 days.

  • Angina, especially if brought on by sex.

  • Heart failure of NYHA Class 2 or worse in the past six months.

  • Uncontrolled irregular heartbeat or uncontrolled blood pressure.

  • Blood pressure below 90/50.

  • Aortic stenosis or another outflow obstruction.

  • A curved or deformed penis, such as Peyronie’s disease.

  • Any past erection lasting beyond four hours.

  • Sickle cell anaemia, myeloma or leukaemia.

  • Retinitis pigmentosa or any past sudden vision loss.

  • Bleeding disorders or an active stomach ulcer.

  • Liver or kidney impairment of any degree.

  • Diabetes, if you are watching sugar. The gel is sweetened.

Food, drink and the gel itself

  • Food does not affect absorption. Eat as you like.

  • Avoid grapefruit and grapefruit juice, which raise tadalafil levels.

  • Keep alcohol low. Both alcohol and tadalafil widen blood vessels.

  • Five or more drinks with tadalafil can drop standing blood pressure.

  • Advice that moderate alcohol is simply acceptable overstates the case.

  • Alcohol also makes erections harder to achieve on its own.

  • The gel contains sugar and flavouring. Mention diabetes to your doctor.

  • Never combine this with poppers in any setting.

Before-use checklist

  • Do I hold a valid prescription for 20 mg specifically?

  • Have I taken tadalafil before, and at what dose?

  • Has my swallowing difficulty been discussed with a doctor?

  • Am I certain I take no nitrate, including a spray or patch?

  • Am I free of riociguat and of poppers?

  • Are my liver and kidneys healthy?

  • Am I clear of ketoconazole, itraconazole and ritonavir?

  • Has my heart been assessed as fit for sexual activity?

  • Is this sachet sealed and in date?

  • Has a full 24 hours passed since my last sachet?

  • Do I know not to dilute it in a drink?

Side Effects

EffectPlacebo10 mg20 mg
Headache5%11%15%
Indigestion1%8%10%
Back pain3%5%6%
Muscle ache1%4%3%
Blocked nose1%3%3%
Flushing1%3%3%
Limb pain1%3%3%
  • These are the same rates as the tablet. The format changes nothing here.

  • Headache is the commonest complaint at this strength.

  • Indigestion matters more if you already have reflux.

  • Tadalafil can aggravate reflux, which is itself a cause of swallowing trouble.

  • Mention existing reflux to your doctor before starting.

  • Across trials, 3.1 percent stopped due to side effects, versus 1.4 on placebo.

The delayed backache

  • It appears 12 to 24 hours after the dose, not straight away.

  • Men describe a diffuse ache low in the back, buttocks or thighs.

  • Lying flat often makes it more noticeable.

  • It usually clears within 48 hours.

  • Ordinary painkillers helped most men who tried them.

  • No muscle, kidney or joint damage was found behind it.

  • About 1 man in 200 stopped treatment because of it.

Uncommon and rare effects

WhereWhat has been reported
CirculationChest discomfort, palpitations, racing pulse, low pressure, fainting
Circulation, rareHeart attack, sudden cardiac death, stroke
VisionBlurring, altered colour, sore or red eyes, swollen lids
Vision, rareNAION, blocked retinal vessels, visual field loss
HearingTinnitus, sudden partial or complete hearing loss
Head and nervesDizziness, vertigo, sleeplessness, numbness, migraine, seizure, memory blanks
Stomach and gutDry mouth, nausea, vomiting, reflux, gastritis, altered liver blood tests
Joints and muscleAching joints, stiff neck, cramping
Genital and urinaryProlonged erection, priapism, unprompted erections, kidney impairment
BreathingBreathlessness, nosebleeds, sore throat
SkinRash, itch, sweating, nettle rash
Skin, rareStevens-Johnson syndrome, peeling dermatitis

Drug Interactions – Avoid With

SeveritySubstanceConsequence
ABSOLUTE BANNitrates in any form: tablets, sprays, patches, ointmentsBlood pressure can collapse. Deaths have occurred.
ABSOLUTE BANPoppers: amyl nitrite and similarIdentical danger
ABSOLUTE BANRiociguat and guanylate cyclase stimulatorsUnsafe blood pressure fall
ABSOLUTE BANSildenafil, vardenafil or another PDE-5 inhibitorNo added benefit, compounded pressure drop
ABSOLUTE BANAny other tadalafil product, tablet or jellySilent doubling of the dose
DOSE CONFLICTKetoconazole 400 mg dailyExposure rises 312%; ceiling becomes 10 mg per 72 hours
DOSE CONFLICTRitonavir 200 mg twice dailyExposure rises 124%; ceiling becomes 10 mg per 72 hours
DOSE CONFLICTItraconazole and other strong CYP3A4 blockersCeiling becomes 10 mg. This sachet is 20 mg.
CAUTIONAlpha-blockers: doxazosin, tamsulosin, alfuzosinDizziness, fainting, low pressure on standing
NOT RECOMMENDEDAlpha-blockers where BPH is the condition treatedThe pairing was not adequately studied
CAUTIONBlood pressure medicines including ARBsA further fall of roughly 8/4 mmHg
CAUTIONAlcohol, five drinks or moreDizziness, headache, low pressure on standing
WEAKENS ITRifampicinExposure falls 88%. The sachet may not work.
WEAKENS ITBosentan, carbamazepine, phenytoin, phenobarbitalExposure falls
MINORAntacidsSlower absorption, unchanged total exposure
MINORGrapefruit juiceRaises exposure
  • Warfarin, midazolam and digoxin were not meaningfully affected.

  • The three DOSE CONFLICT rows cap the dose at 10 mg.

  • This sachet is double that and cannot be divided.

  • Those men need a 10 mg tablet instead.

  • Show a doctor a written list of everything you take.

Emergency Warning Signs

  • An erection still present after four hours, painful or not.

  • Four hours is the label threshold. Acting sooner does no harm.

  • Untreated, the tissue scars and erectile function can be lost.

  • Sudden loss of vision in one eye or both.

  • Sudden loss or reduction of hearing, with or without ringing.

  • Chest pain, tightness, or pain into arm, neck or jaw.

  • Feeling faint or unwell during sex. Stop immediately.

  • Fainting, or severe dizziness on standing.

  • Slurred speech, a drooping face, or one-sided weakness.

  • Swelling of the face, lips, tongue, or throat.

  • Coughing, choking or breathlessness after taking the gel.

  • A rash that spreads, blisters or peels.

  • A seizure.

Why Choose Tadarise Oral Jelly

What holds up

  • It solves a real problem for men who cannot swallow tablets.

  • No water is needed, which helps if your mouth is dry.

  • The flavour masks the taste of the drug.

  • Each sachet is pre-measured, so nothing needs counting.

  • Sachets are flat, sealed and discreet to carry.

  • 20 mg is the approved ceiling, not above it.

  • Tadalafil offers the longest window among common ED treatments.

  • Food does not interfere with it at all.

  • It has helped men with diabetes-related ED in trials.

  • It has helped men after nerve-sparing prostate surgery.

What does not hold up

  • It does not bypass digestion. Tadalafil will not cross the mouth lining.

  • No published study shows it acts faster than a tablet.

  • It does not work in 10 to 15 minutes.

  • It does not last 48 hours. The figure is 36.

  • It is not a treatment for lung artery pressure at this dose.

  • It cannot serve a first-time user, since 10 mg is the starting dose.

  • It is not FDA, EMA or MHRA approved.

Storage Instructions

  • Keep below 30 °C, as Indian packs specify.

  • US tadalafil labelling gives 25 °C, tolerating 15 to 30 °C.

  • Leave each sachet sealed until the moment you use it.

  • Moisture is the main enemy of a gel sachet.

  • Bathrooms swing through humidity all day. Store elsewhere.

  • Keep away from direct sun and any heat source.

  • A parked car in an Indian summer will exceed the safe range.

  • Do not refrigerate, and never freeze.

  • An opened sachet cannot be saved. Discard leftover gel.

  • Do not use a sachet that is leaking, swollen, split or discoloured.

  • Keep well out of children’s sight and reach.

  • A fruit-flavoured gel sachet looks very like a sweet.

  • Store the box in a locked or high cupboard for that reason.

  • Do not use past the printed expiry date.

  • Return unused sachets to a pharmacy.

  • Never share this medicine with anyone.

Sanjay Gangani

Sanjay Gangani

B.Pharm, CMO & Pharmacist

Licensed pharmacist (B.Pharm) with 12+ years in clinical pharmacy and patient care. Reviews every article for evidence-based accuracy before it is published on ACTIZA Store.

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