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Natcolan 500 Mg (Lanthanum Carbonate)
Medically reviewed by Sanjay Gangani, B.Pharm, CMO & Pharmacist
| Active Ingredient | Lanthanum Carbonate |
|---|---|
| Indication | hyperphosphatemia |
| Manufacturer | Natco Pharma Ltd. |
| Strength:- | 500mg |
| Packaging | 45 tablets in 1 bottle |
Natcolan 500 Mg (Lanthanum Carbonate) | ||||
|---|---|---|---|---|
| Pack Size | Price | Quantity | Add To Cart | |
| 45 Tablet/s | $38 | |||
| 90 Tablet/s | $69.2 | |||
| 180 Tablet/s | $124.56 | |||
What is Natcolan 500 mg?
How It Works (Mechanism of Action)
Dosage Guide
Your nephrology team sets your dose, titrated against your blood phosphate results.
| Point | Guidance |
|---|---|
| Recommended initial total daily dose | 1,500 mg, divided across meals |
| Titration | Adjusted every 2 to 3 weeks against serum phosphate |
| Available strengths | 500 mg, 750 mg and 1,000 mg |
| Timing | With or immediately after meals |
| Administration | Chew or crush completely before swallowing |
| Dividing the dose | Total daily dose split across meals |
| Other medicines | Avoid 1 hour before or 3 hours after |
| Bowel obstruction | Contraindicated |
| Severe constipation | Do not use |
| Children | Not established |
| Monitoring | Serum phosphate; also calcium, folic acid and fat-soluble vitamins |
Do not adjust your own dose. Phosphate binder dosing is titrated against blood results and your diet.
How to Take It
Precautions
Do Not Use If You
Tell Your Doctor Before Taking If You Have
Practical Precautions
| Item | Consideration |
|---|---|
| Chewing | Essential for both effect and safety |
| Meal timing | With or immediately after food |
| Other medicines | Avoid 1 hour before or 3 hours after |
| Constipation | Report early; can progress to obstruction |
| Diet | Follow your prescribed phosphate diet |
| Vitamin levels | Calcium, folic acid and vitamins A, D, E and K may fall |
| Abdominal X-rays | Lanthanum is radio-opaque and may appear on imaging |
| Difficulty chewing | Tell your prescriber crushing or a powder form may suit better |
Before-Starting Checklist
Side Effects
The most common adverse reactions are gastrointestinal events.
| Side Effect | Notes |
|---|---|
| Nausea | Very common |
| Vomiting | Common |
| Constipation | Common; report early – can progress |
| Abdominal pain | Common |
| Diarrhoea | Common |
| Indigestion | Common |
| Headache | Reported |
| Low blood calcium | Monitored; supplements may be needed |
| Low folic acid | Monitored |
| Low vitamins A, D, E and K | Monitored |
| Gastrointestinal obstruction | Serious – see section 7 |
| Ileus or subileus | Serious – see section 7 |
| Gastrointestinal perforation | Serious – see section 7 |
| Faecal impaction | Serious – see section 7 |
| Acute pancreatitis | Reported in clinical studies |
| Tooth or dental problems | Reported with chewable tablets |
| Allergic reactions | Stop and seek advice |
Emergency Warning Signs
Seek urgent medical care if you develop:
Signs of bowel obstruction or perforation:
What to Know About This Medicine
What lanthanum carbonate offers:
Important limitations:
Storage Instructions
Medical Disclaimer
This content is for information only. It is not medical advice. Natcolan 500 mg contains lanthanum carbonate, a phosphate binder, and is a prescription-only medicine used to control blood phosphate levels in patients with chronic kidney disease, particularly those on dialysis.
Chew or crush the tablets completely before swallowing. Do not swallow them whole. Phosphate binding depends on the surface area created by chewing, and swallowing tablets whole reduces effectiveness and increases the risk of gastrointestinal obstruction.

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