Anobliss Cream (Lidocaine/Nifedipine) Medically reviewed by Sanjay Gangani, B.Pharm, CMO & Pharmacist
Active Ingredient Lidocaine/Nifedipine Indication Local anesthesia (Numb tissues in a specific area), Anal fissure Manufacturer Samarth Life Sciences Pvt Ltd Strength:- 30g Dosage Form:- Gel Packaging 30 gm in 1 tube Country of Origin India
INQUIRE ABOUT Anobliss Cream (Lidocaine/Nifedipine)
What is Anobliss Cream? Anobliss is a prescription cream for anal problems.
It contains nifedipine 0.3% w/w.
It also contains lidocaine 1.5% w/w.
Nifedipine is a calcium channel blocker.
Lidocaine is a local anaesthetic.
It comes as a tube of 30 grams.
Managing acute anal fissures, meaning a tear in the lining.
Relieving pain, irritation or itching from that tear.
Reducing discomfort from haemorrhoids.
Easing discomfort during rectal examinations.
Relieving pain after anal surgery.
Anorelief cream, Fidonal cream and Xylocaine NF cream.
Another names Anasdee NF as 25 percent cheaper.
Others listed are Anomed L, Nifedip LA and Anozest.
How the Two Medicines Work A fissure is a tear in the lining of the anus.
The muscle ring around the anus goes into spasm.
That spasm reduces blood flow to the tear.
Poor blood flow stops the tear from healing.
Nifedipine relaxes that muscle and widens the vessels.
One listing says the cream relaxes blood vessels in the anus.
It says this helps the fissure heal.
A listing for a related cream explains the same cycle.
It describes reduced anal pressure and increased blood flow.
It blocks pain signals from the nerves to the brain.
That reduces pain, which itself worsens the spasm.
Numbing and relaxing therefore work together.
Dosage Guide No listing publishes a numeric dose or frequency.
Item What the Sources Say Who Decides Key Note Dose and frequency Consult your doctor The prescriber Stated on one listing Duration For as long as prescribed The prescriber Stated on one listing How to apply Sources disagree The pack insert See the notice above Hands Wear gloves while applying The patient Stated on one listing Other creams Do not apply another at the same site The patient Stated on one listing By mouth Never Not applicable It is not an oral medicine Eyes, mouth and nose Avoid contact The patient Stated on one listing Missed application Apply as soon as possible The patient Stated on two listings Overdose Unlikely with external use Not applicable Stated on one listing Severe kidney disease Use with caution The prescriber A dose change may be needed
Why no frequency appears here:
None of the sources consulted gives one.
No regulatory label for this product was retrieved.
Fissure creams are often applied two or three times daily.
That is a general pattern, not this product’s instruction.
Take the frequency from your prescription.
How to Apply It – The Open Question The sources give two different methods.
Source What It Says Implication One pharmacy listing For external use only Applied around the opening Another pharmacy listing For administration into the rectum Inserted internally The same listing Use the applicator provided Implies a measured internal dose A related diltiazem cream For external use only Supports the external method That same related listing Use a finger film or glove Applied by finger, externally
What is agreed across the sources:
It must never be taken by mouth.
Contact with eyes, mouth and nose must be avoided.
Gloves or a finger covering should be used.
Hands should be washed afterwards.
No other cream should be applied to the same area.
Internal insertion places the cream against absorbent lining.
More of both medicines can then reach the bloodstream.
Nifedipine lowers blood pressure when absorbed.
Lidocaine affects the heart and nerves at higher levels.
External application limits that absorption.
Follow the instruction printed on your own pack.
Precautions Tell Your Doctor Before Use If You: Are pregnant, especially in the first three months.
Are breastfeeding.
Have severe kidney disease .
Have liver disease.
Have low blood pressure.
Have any heart condition.
Are allergic to local anaesthetics.
Take any other medicine, including other creams.
One says consult your doctor, especially in the first trimester.
Another says the cream may be unsafe in pregnancy.
Another says it is probably unsafe while breastfeeding.
Those positions differ in strength and should be checked.
Practical Points From the Listings Wear gloves to reduce the chance of side effects.
Do not apply any other medicine to the same area afterwards.
The cream does not affect driving ability.
Light-headedness is reported for this class of cream.
A related listing advises against alcohol during treatment.
Do not stop early without consulting your doctor.
Before-Use Checklist Has a doctor diagnosed an anal fissure?
Do you have the pack insert with your tube?
Does it say external application or insertion?
Do you know how many times a day to apply it?
Do you have gloves or finger coverings?
Are you pregnant or breastfeeding?
Do you have kidney, liver or heart problems?
Do you know not to apply other creams to the area?
Side Effects Effects named across the listings:
Side Effect Category What It Feels Like What to Do Anal irritation Common Burning or stinging at the site Report if persistent Light-headedness Reported Feeling faint Sit down; report it Headache Class effect Head pain Report if persistent Local redness Class effect Reddened skin Report if it worsens Numbness beyond the site Class effect Wider loss of sensation Report to your doctor Low blood pressure With absorption Dizziness on standing Report to your doctor Allergic skin reaction Reported Rash or itching Stop and seek advice Severe allergic reaction Rare Swelling, breathlessness Emergency – seek care
How to read this table:
Only two effects are named on the Indian listings.
Those are anal irritation and light-headedness.
The rest are recognised effects of the two drug classes.
None is quoted from a regulatory label.
No frequency figures exist for any of them.
Check the pack insert for the full list.
Warning Signs – Seek Medical Help Seek urgent medical care if you have:
Swelling of the face, lips or throat.
Difficulty breathing.
Fainting, or a collapse.
A racing or irregular heartbeat.
Numbness spreading well beyond the treated area.
Heavy bleeding from the back passage.
Pain worsens rather than settling.
The area becomes hot, swollen or discharging.
Bleeding continues after several days of treatment.
You feel dizzy whenever you stand.
The fissure has not improved by the end of the course.
A fissure that does not heal may need surgical review.
Persistent bleeding needs a cause to be established.
A cream should not be continued indefinitely alone.
An Honest Assessment for the Retailer What can fairly be said:
The two ingredients address the fissure cycle sensibly.
Nifedipine relaxes the muscle and improves blood flow.
Lidocaine relieves the pain that worsens the spasm.
The composition is consistent across all sources.
The tube is inexpensive at about five rupees per gram.
Several same-composition alternatives exist.
Whether it is applied externally or inserted.
How many times a day it should be applied.
Who actually manufactures it.
Which of three storage statements applies.
Whether it heals a fissure or only relieves symptoms.
All five answers should come from the pack insert.
Storage – Three Different Statements Source Storage Given Company Named Indian pharmacy Store below 30°C Samarth Life Sciences Indian pharmacy Store below 25°C Not stated there Export listing one Store below 25°C Blossom Pharmaceuticals Export listing two Store at 15 to 25°C Sankalp Healthcare
Those are three different requirements for one product.
A range of 15 to 25 degrees is the narrowest of them.
Below 30 degrees is the most permissive.
The difference affects storage, packing and shipping.
Confirm the statement printed on your own carton.
Keep the tube capped and out of reach of children.
Check the expiry date before use.
Sanjay Gangani
B.Pharm, CMO & Pharmacist
Licensed pharmacist (B.Pharm) with 12+ years in clinical pharmacy and patient care. Reviews every article for evidence-based accuracy before it is published on ACTIZA Store.
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