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Tadacip 20 Mg (Tadalafil)
Medically reviewed by Sanjay Gangani, B.Pharm, CMO & Pharmacist
| Active Ingredient | Tadalafil |
|---|---|
| Indication | Erectile Dysfunction |
| Manufacturer | Cipla Limited |
| Strength:- | 20mg |
| Packaging | 10 tablets in 1 strip |
Tadacip 20 Mg (Tadalafil) | ||||
|---|---|---|---|---|
| Pack Size | Price | Quantity | Add To Cart | |
| 90 Tablet/s | $90 | |||
| 120 Tablet/s | $111 | |||
| 180 Tablet/s | $160 | |||
| 300 Tablet/s | $250 | |||
What is Tadacip 20 mg?
How It Works (Mechanism of Action)
Dosage Guide
A doctor sets the dose. This reflects approved tadalafil labelling.
| Situation | Licensed dose | Frequency | Does Tadacip 20 fit? |
|---|---|---|---|
| Established on 10 mg, response insufficient | 20 mg | Once in 24 hours | Yes. This is the intended user. |
| First time taking tadalafil | 10 mg | Once in 24 hours | No. Begin at 10 mg. |
| 10 mg worked but caused headache | 5 mg | Once in 24 hours | No. Four times the needed dose. |
| Wanting a daily routine | 2.5 to 5 mg | Every day | No. 20 mg is never a daily dose. |
| Prostate and urinary symptoms | 5 mg | Every day | No. Wrong strength and regimen. |
| Moderate kidney impairment | 10 mg maximum | Once in 48 hours | No. Double the ceiling. |
| Severe kidney impairment | 5 mg maximum | Once in 72 hours | No. Four times the ceiling. |
| Mild or moderate liver impairment | 10 mg maximum | Once in 24 hours | No. Double the ceiling. |
| Severe liver impairment | Not recommended | Not applicable | No. Do not use. |
| On potent CYP3A4 inhibitors | 10 mg maximum | Once in 72 hours | No. Double the ceiling. |
| Aged over 65 | No change for age alone | Once in 24 hours | Possibly. Sensitivity may be greater. |
| Women, children, under-18s | Not indicated | Not applicable | No. |
How to Take It
What to expect on the first occasion
Precautions
Absolute contraindications
Tell your doctor about
Food, drink and lifestyle
Before-use checklist
Side Effects
Common effects
From tadalafil trials. The 20 mg column applies to this tablet.
| Effect | Placebo | 10 mg | 20 mg |
|---|---|---|---|
| Headache | 5% | 11% | 15% |
| Indigestion | 1% | 8% | 10% |
| Back pain | 3% | 5% | 6% |
| Muscle ache | 1% | 4% | 3% |
| Blocked nose | 1% | 3% | 3% |
| Flushing | 1% | 3% | 3% |
| Limb pain | 1% | 3% | 3% |
Uncommon and rare effects
| Where | What has been reported |
|---|---|
| Circulation | Chest discomfort, palpitations, racing pulse, low pressure, fainting |
| Circulation, rare | Heart attack, sudden cardiac death, stroke |
| Vision | Blurring, altered colour, sore or red eyes, swollen lids |
| Vision, rare | NAION, blocked retinal vessels, visual field loss |
| Hearing | Tinnitus, sudden partial or complete hearing loss |
| Head and nerves | Dizziness, vertigo, sleeplessness, numbness, migraine, seizure, memory blanks |
| Stomach and gut | Dry mouth, nausea, vomiting, reflux, gastritis, altered liver blood tests |
| Joints and muscle | Aching joints, stiff neck, cramping |
| Genital and urinary | Prolonged erection, priapism, unprompted erections |
| Breathing | Breathlessness, nosebleeds, sore throat |
| Skin | Rash, itch, sweating, nettle rash |
| Skin, rare | Stevens-Johnson syndrome, peeling dermatitis |
Drug Interactions – Avoid With
| Severity | Substance | Consequence |
|---|---|---|
| ABSOLUTE BAN | Nitrates in any form: tablets, sprays, patches, ointments | Blood pressure can collapse. Deaths have occurred. |
| ABSOLUTE BAN | Poppers: amyl nitrite and similar | Identical danger |
| ABSOLUTE BAN | Riociguat and guanylate cyclase stimulators | Unsafe blood pressure fall |
| ABSOLUTE BAN | Sildenafil, vardenafil or another PDE-5 inhibitor | No added benefit, compounded pressure drop |
| ABSOLUTE BAN | Any other tadalafil product, including lung-pressure brands | Silent doubling of the dose |
| DOSE CONFLICT | Ketoconazole 400 mg daily | Exposure rises 312%; ceiling becomes 10 mg per 72 hours |
| DOSE CONFLICT | Ritonavir 200 mg twice daily | Exposure rises 124%; ceiling becomes 10 mg per 72 hours |
| DOSE CONFLICT | Itraconazole and other strong CYP3A4 blockers | Ceiling becomes 10 mg. This tablet is 20 mg. |
| CAUTION | Alpha-blockers: doxazosin, tamsulosin, alfuzosin | Dizziness, fainting, low pressure on standing |
| CAUTION | Blood pressure medicines including ARBs | A further fall of roughly 8/4 mmHg |
| CAUTION | Alcohol, five drinks or more | Dizziness, headache, low pressure on standing |
| WEAKENS IT | Rifampicin | Exposure falls 88 percent. The tablet may not work. |
| WEAKENS IT | Bosentan, carbamazepine, phenytoin, phenobarbital | Exposure falls |
| MINOR | Antacids | Slower absorption, unchanged total exposure |
| MINOR | Grapefruit juice | Raises exposure |
| NO INTERACTION | Warfarin, midazolam, digoxin | No meaningful effect found |

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