Super Hiforce 50 (Sildenafil/Dapoxetine)

Super Hiforce 50 is a combination tablet with two active ingredients.

It contains sildenafil 50 mg, a PDE-5 inhibitor for erectile dysfunction.

It also contains dapoxetine 30 mg, a short-acting SSRI for premature ejaculation.

It is intended for men who have both conditions together.

Sildenafil helps achieve and maintain a firm erection.

Dapoxetine helps delay ejaculation during intercourse.

Dapoxetine is designed for on-demand use, not daily dosing.

It leaves the body quickly compared with regular antidepressants.

It is made by Healing Pharma in India.

The tablet is swallowed whole with water.

Hiforce 100 mg and Hiforce 150 mg works only during sexual stimulation.

It does not increase sexual desire or libido.

It does not cure either underlying condition.

It offers no protection against HIV or other STIs.

Women and anyone under 18 must not use it.

A full medical assessment should precede treatment.

Sexual stimulation triggers nitric oxide release in penile tissue.

Nitric oxide activates an enzyme called guanylate cyclase.

This enzyme raises cyclic guanosine monophosphate (cGMP) levels.

cGMP relaxes smooth muscle in the corpus cavernosum.

Relaxed muscle lets penile arteries widen and fill with blood.

Expanding tissue compresses the veins, trapping blood inside.

An enzyme called PDE-5 normally breaks cGMP down.

Sildenafil blocks PDE-5, so cGMP stays elevated longer.

Blood flow is therefore maintained during sexual activity.

Ejaculation is controlled by a spinal reflex.

Serotonin signalling in the brain and spinal cord regulates this reflex.

Nerve cells release serotonin, then reabsorb it quickly.

Dapoxetine blocks the transporter that reabsorbs serotonin.

Serotonin therefore stays active in the synapse longer.

Increased signalling raises the ejaculatory threshold.

This delays the ejaculation reflex during intercourse.

Dapoxetine is absorbed and cleared rapidly.

This makes it suitable for on-demand use only.

Dapoxetine is a selective serotonin reuptake inhibitor. It does not act on dopamine, and it is not a serotonin-norepinephrine reuptake inhibitor. Some product listings state otherwise. The distinction matters because dapoxetine interacts with other serotonin-affecting medicines.

Dapoxetine 30 mg increased time to ejaculation roughly two to three times over baseline in clinical studies. Individual results vary considerably.

Sildenafil works best 30 to 60 minutes before sex. Dapoxetine works best 1 to 3 hours before. A single tablet cannot optimise both. Around 1 hour beforehand is the usual compromise.

Drink a full glass of water with the tablet. This reduces fainting risk.

The sildenafil effect lasts around 4 to 5 hours.

Take it only when sexual activity is planned.

Not applicable. This medicine is used only as needed.

Your doctor should reassess after about 4 weeks or 6 doses.

Take the tablet exactly as your doctor prescribed.

Check the pack shows sildenafil 50 mg and dapoxetine 30 mg.

Swallow the tablet whole with a full glass of water.

Do not chew, crush, or split the tablet.

A combination tablet cannot be divided reliably.

Take it approximately 1 hour before planned sexual activity.

Stay well hydrated before and after the dose.

It may be taken with or without food.

Avoid heavy or high-fat meals for faster sildenafil onset.

Sexual stimulation is required for the erection effect.

Take no more than one tablet in 24 hours.

Do not take it daily unless your doctor directs otherwise.

Do not combine it with any other ED or PE medicine.

Sit or lie down immediately if you feel faint.

Do not drive or operate machinery after dosing.

Attend your doctor’s review appointment as arranged.

Do not share your tablets with anyone else.

Take any nitrate medicine in any form.

Nitrates include glyceryl trinitrate and isosorbide mononitrate or dinitrate.

This covers nitrate sprays, patches, and sublingual tablets.

Take nicorandil, a nitrate-like anti-anginal medicine.

Use amyl nitrite or butyl nitrite recreationally (“poppers”).

Take riociguat or another guanylate cyclase stimulator.

Have had a heart attack or stroke within 6 months.

Have unstable angina or angina during sexual intercourse.

Have severe low blood pressure below 90/50 mmHg.

Have severe uncontrolled high blood pressure.

Have retinitis pigmentosa or another inherited retinal disease.

Have previously lost vision from non-arteritic anterior ischaemic optic neuropathy (NAION).

Have any significant heart valve disease.

Have heart failure classified as NYHA class II, III, or IV.

Have a heart conduction disorder, such as AV block.

Have sick sinus syndrome or a pacemaker for conduction problems.

Have significant ischaemic heart disease.

Have any history of fainting or syncope.

Have a history of mania, hypomania, or bipolar disorder.

Have moderate or severe depression, treated or untreated.

Take a monoamine oxidase inhibitor (MAOI) now or recently.

Have taken an MAOI within the past 14 days.

Take thioridazine, or took it within 14 days.

Take any SSRI, SNRI, or tricyclic antidepressant.

Stopped such an antidepressant less than 14 days ago.

Take lithium, tryptophan, or St John’s Wort.

Take linezolid, tramadol, or a triptan migraine medicine.

Have moderate or severe liver impairment.

Have a history of seizures or epilepsy.

Are allergic to sildenafil, dapoxetine, or any excipient.

Have been advised to avoid sexual activity for cardiac reasons.

Are aged under 18 or over 64.

Are a woman or a child.

Nitrates plus sildenafil can cause a fatal drop in blood pressure. Never combine them. Allow at least 24 hours between a dose and any nitrate.

Wait 14 days after stopping an MAOI or SSRI before using dapoxetine. Wait 7 days after stopping dapoxetine before starting one. Combining them can cause serotonin syndrome,

Any heart disease, arrhythmia, or heart rhythm irregularity.

A previous heart attack, stroke, or bypass surgery.

High blood pressure or low blood pressure.

Dizziness on standing, or orthostatic hypotension.

Any episode of fainting, however long ago.

Any mental health condition, including anxiety or depression.

Any past thoughts of self-harm or suicide.

A family history of bipolar disorder.

Epilepsy or any seizure disorder.

Liver disease or hepatitis of any type.

Kidney disease or reduced kidney function.

Any eye disease or sudden vision loss previously.

Hearing loss, tinnitus, or other ear disorders.

Sickle cell anaemia, leukaemia, or multiple myeloma.

Any bleeding disorder, or use of blood thinners.

An active or recent stomach ulcer.

A penile deformity such as Peyronie’s disease.

Diabetes, especially if poorly controlled.

Any recreational drug use, including nitrites.

Recent or planned surgery, including dental procedures.

Alcohol with dapoxetine significantly raises the risk of fainting and injury. Treat this as an absolute avoid, not a suggestion.

A doctor has prescribed this combination for me.

The pack shows sildenafil 50 mg and dapoxetine 30 mg.

I have discussed my mental health history in full.

I have no history of fainting or heart rhythm problems.

I take no antidepressant of any kind.

I stopped any MAOI or SSRI more than 14 days ago.

I take no tramadol, lithium, triptans, or St John’s Wort.

I have taken no nitrate medicine in 24 hours.

I have not used poppers or amyl nitrite.

I take no ketoconazole, itraconazole, ritonavir, or clarithromycin.

I have taken no other ED or PE medicine today.

I have not taken a dose in the last 24 hours.

I have drunk no alcohol today.

I will drink a full glass of water with the tablet.

I will not drive or operate machinery afterwards.

I am aged between 18 and 64.

The blister is sealed and the expiry date valid.

I know the emergency warning signs listed below.

All nitrates: glyceryl trinitrate, isosorbide mononitrate, isosorbide dinitrate.

Nicorandil, a nitrate-like anti-anginal medicine.

Amyl nitrite and butyl nitrite (“poppers”).

Riociguat and other soluble guanylate cyclase stimulators.

MAOIs: phenelzine, tranylcypromine, isocarboxazid, moclobemide, selegiline.

SSRIs: fluoxetine, sertraline, paroxetine, citalopram, escitalopram.

SNRIs: venlafaxine, duloxetine.

Tricyclic antidepressants: amitriptyline, imipramine, clomipramine.

Thioridazine and other antipsychotics affecting heart rhythm.

Lithium, tryptophan, and St John’s Wort.

Linezolid, an antibiotic with MAOI activity.

Tramadol and other serotonergic painkillers.

Triptans: sumatriptan, rizatriptan, and similar migraine drugs.

Potent CYP3A4 inhibitors: ketoconazole, itraconazole, ritonavir, telithromycin, nefazodone.

Other PDE-5 inhibitors: tadalafil, vardenafil, avanafil.

Other Hiforce products at any strength.

Other dapoxetine products or any other PE treatment.

Recreational drugs, especially MDMA, cocaine, and amphetamines.

Alpha-blockers: tamsulosin, doxazosin, alfuzosin, terazosin.

Moderate CYP3A4 inhibitors: erythromycin, fluconazole, diltiazem, verapamil.

Blood pressure medicines, including diuretics and calcium channel blockers.

Warfarin and other anticoagulants.

NSAIDs and aspirin, due to bleeding risk with SSRIs.

Any medicine affecting heart rhythm or the QT interval.

Cimetidine, an acid-reducing medicine.

Rifampicin, an antibiotic used for tuberculosis.

Carbamazepine, phenytoin, and phenobarbital.

Fainting, blackout, or loss of consciousness.

Severe dizziness where you cannot stay standing.

A very slow or irregular heartbeat.

Chest pain, pressure, or tightness during or after sex.

Pain spreading to the jaw, neck, or left arm.

An erection lasting longer than 4 hours (priapism).

A painful erection that will not subside.

Sudden loss of vision in one or both eyes.

Sudden decrease or loss of hearing.

Swelling of the face, lips, tongue, or throat.

Widespread rash with blistering or peeling skin.

A seizure or convulsion.

Signs of stroke: sudden weakness, slurred speech, facial droop.

Agitation, confusion, or restlessness.

Muscle twitching, stiffness, or loss of coordination.

Rapid heartbeat with high blood pressure.

Heavy sweating with fever or shivering.

Severe diarrhoea with nausea and vomiting.

New or worsening thoughts of suicide or self-harm.

Sudden severe low mood or hopelessness.

Unusually elevated mood, racing thoughts, or reckless behaviour.

Tell emergency staff what you have taken. Name both sildenafil and dapoxetine, and state the doses as 50 mg and 30 mg. They must not give you nitrate medicines. Untreated priapism can cause permanent erectile damage within hours.

Both components are at their recommended starting doses.

Sildenafil 50 mg is the standard first dose for ED.

Dapoxetine 30 mg is the standard first dose for PE.

The 100 and 160 versions use dapoxetine 60 mg instead.

Starting lower reduces the chance of side effects.

Treats erectile dysfunction and premature ejaculation in one tablet.

Removes the need to manage two separate prescriptions.

Both molecules are individually well studied.

Dapoxetine is designed specifically for on-demand use.

It clears the body faster than standard antidepressants.

Healing Pharma offers the range at several strengths.

The fixed combination is not approved by the FDA, EMA, or MHRA.

Dapoxetine has never been approved in the United States.

A single tablet cannot optimise timing for both drugs.

Dapoxetine adds fainting risk that sildenafil alone does not carry.

Dapoxetine adds significant mental health contraindications.

Its interaction list is far longer than for sildenafil alone.

It is unsuitable for men over 64.

Neither component can be dose-adjusted independently.

The range numbering invites confusion between strengths.

Many equivalent products share this exact composition.

You have erectile dysfunction without premature ejaculation.

You have premature ejaculation without erectile dysfunction.

You need different dose adjustments for each condition.

You have any cardiac or mental health history listed above.

You are aged 65 or over.

For men with both conditions and no contraindications, this is a sensibly dosed combination. Check the component strengths on the pack, and settle the dapoxetine contraindications with a doctor first.

Store below 30°C in a cool, dry place.

Protect tablets from direct sunlight and heat.

Keep tablets sealed in the original blister until use.

Do not store in the bathroom or near a sink.

Moisture and humidity can degrade the tablets.

Do not transfer tablets into unlabelled containers.

Keep the original pack for both drug names and strengths.

Never store these alongside other Hiforce products.

The range includes several different strengths.

Confusing them could double your dapoxetine dose.

Do not freeze or refrigerate this product.

Keep it out of the sight and reach of children.

Accidental ingestion by a child is a medical emergency.

Check the expiry date printed on the pack.

Never use tablets after the expiry date.

Discard damaged, cracked, or discoloured tablets.

Dispose of unused medicine through a pharmacy take-back scheme.

Do not flush tablets or throw them in household waste.