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Promethazine Hydrochloride Tablets are anti-allergic medications that are indicated for treatment of various allergies, nausea, and sleeping trouble. They are also known to find application as sedative with ability to treat cough in combination with dextromethorphan. Active chemical used in their formulation has molecular formula C17H21ClN2S with molar mass of 320.879 g/mol with around 88% of bioavailability. Having protein binding ability of 93%, these tablets get metabolized with help of glucuronidation & sulfoxidation in liver. Promethazine Hydrochloride Tablets is considered as a strong antihistamine H1 receptor antagonist with ability to serve as local anesthetic agent.
Uses : Promethazine is used in the treatment of allergic disorders
How it works : Promethazine blocks the action of certain chemical messengers that are responsible for inflammation, congestion, itching, and other allergic reactions.
Common side effects : Nightmare, Pale red skin, Itchy rash, Rash, Abdominal cramp, Abnormal liver function tests, Altered heart rate, Blurred vision, Confusion, Decreased blood pressure, Diarrhoea, Disorientation (alteration of mental status),