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Diclofenac Injection is an anti-inflammatory and analgesic medication that is administered via intravenous or intramuscular route by trained physician. It is prescribed for providing relief from pain caused due to rheumatoid arthritis, osteoarthritis, musculoskeletal disorders, spondylarthritis, and polymyositis. Active chemical present in this injection has molecular formula C14H11Cl2NO2 with molar mass of 296.148 g/mol. It is known to work by acting on cyclooxygenase enzyme which produces prostaglandins that are responsible for causing pain & inflammation. Diclofenac Injection shows more than 99% of protein binding ability with metabolism in liver by CYP2C9. With elimination half life of 1.2 to 2 hours, it is excreted in urine.
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Diclofenac sodium injection is used in fever, headache, arthralgia, myalgia, dental pain, post operative pain, pain during menstruation, osteoarthritis, rheumatoid arthritis, ankylosing spondylitis and gout.
How it works
Diclofenac sodium injection is a non-steroidal anti-inflammatory drug (NSAID). It works by blocking the release of certain chemical messengers that cause fever, pain and inflammation (redness and swelling).