Bosentan Tablets are prescribed for treatment of pulmonary artery hypertension and for reducing number of digital ulcers. They are competitive antagonist of endothelin-1 receptors which works by decreasing pulmonary vascular resistance. These tablets show bioavailability of about 50% and get metabolized with help of CYP3A4, CYP2C9, and CYP2C19 enzymes. Bosentan has chemical formula C27H29N5O6S with molecular weight of 551.614 g/mol and elimination half-life of about 5 hours. Bosentan Tablets are admired for having protein binding ability of more than 98% having high affinity for ET-A as compared to that for ET-B.
|Minimum Order Quantity||50 Box|
|Dose/Strength (ex. 1 mg or 1ml)||62.5mg, 125mg|
|Packaging Size||100 Tablets|
|Packaging Type||Strips, Box|
|Usage||Clinical, Hospital, Personal|
Bosentan Tablets exporter, Bosentan Tablets manufacturer
Bosentan Tablets supplier, Bosentan Tablets manufacturer in India,Bosentan Tablets exporter in India.