
Amitryptyline HCI Tablets IP have been indicated for major depressive disorder, neuropathic pain, and attention deficit hyperactivity disorder. Active compound present in this medicine has molecular formula C20H23N with molar mass of 277.403 g/mol. With bioavailability of 30 to 60%, they get metabolized in liver by CYP2C9 having excellent protein binding ability of about 96%. Amitryptyline HCI Tablets IP are tricyclic antidepressants that show their strong activity on serotonin transporter. After ingestion, they rapidly get absorbed from GI tract and metabolized in liver with help of CYP2D6 and CYP2C19 enzymes.
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